Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132857 | 1.00 | USP2 (0.62) | USP2KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL6132666 | 0.96 | USP2 (0.57) | USP2KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL6132323 | 0.96 | USP2 (0.57) | USP2KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL6132668 | 0.96 | USP2 (0.57) | USP2KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL6132320 | 0.96 | USP2 (0.57) | USP2KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL607498 | 0.95 | USP2 (0.58) | USP2KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL13069950 | 0.82 | MAPT (0.54) | USP2KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL6132774 | 0.81 | GFER (0.59) | USP2KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL6132772 | 0.81 | GFER (0.59) | USP2KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL6132936 | 0.81 | CSNK2A2 (0.48) | USP2MAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |