Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 5/20 | 0.54 |
| ▸ | HTR6 | P50406 | 3/20 | 0.50 |
| ▸ | HTR3A | P46098 | 3/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.50 |
| ▸ | HTR3B | O95264 | 2/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR5A | P47898 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132413 | 1.00 | ADRB1 (0.54) | ADRB1HTR6HTR3AHTR3EHTR3B | |
| SCHEMBL6582487 | 0.89 | ADRB1 (0.59) | ADRB1HTR6HTR3AHTR3EHTR3B | |
| SCHEMBL15834279 | 0.80 | ADRB1 (0.75) | ADRB1HTR6HTR3AHTR3EHTR3B | |
| SCHEMBL6132417 | 0.79 | ADRB1 (0.56) | ADRB1HTR6HTR3AHTR3EHTR3B | |
| SCHEMBL6132422 | 0.79 | ADRB1 (0.56) | ADRB1HTR6HTR3AHTR3EHTR3B | |
| SCHEMBL17276365 | 0.74 | ADRB1 (0.67) | ADRB1HTR6HTR3AHTR3EHTR3B | |
| SCHEMBL22652955 | 0.74 | ADRB1 (0.67) | ADRB1HTR6HTR3AHTR3EHTR3B | |
| SCHEMBL3070877 | 0.74 | KMT2A (0.56) | LMNAMAPTTSHRHSD17B10KDM4E | |
| SCHEMBL2771146 | 0.74 | KMT2A (0.56) | LMNAMAPTTSHRHSD17B10KDM4E | |
| SCHEMBL3090131 | 0.74 | KMT2A (0.56) | LMNAMAPTTSHRHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |