Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7320929 | 0.90 | ALDH1A1 (0.42) | POLBALDH1A1OPRM1OPRD1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL6937886 | 0.89 | TP53 (0.42) | TP53CA12CA1CA2CA9 | |
| Trifluoroacetic Acid SCHEMBL6135147 | 0.87 | MAPT (0.41) | POLBALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL6134926 | 0.84 | HRH3 (0.46) | POLBALDH1A1OPRM1OPRD1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL7318099 | 0.84 | F2RL3 (0.41) | TP53DPP4DPP7THRBCA12 | |
| Trifluoroacetic Acid SCHEMBL6135113 | 0.83 | MAPT (0.40) | TP53DPP4DPP7FDFT1CA12 | |
| Hydrochloric Acid SCHEMBL6132465 | 0.83 | TP53 (0.46) | POLBTP53CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL6132355 | 0.83 | MAPT (0.38) | POLBALDH1A1TP53DPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL7325659 | 0.83 | SIRT2 (0.46) | ALDH1A1TP53THRBCA12CA1 | |
| Trifluoroacetic Acid SCHEMBL6132999 | 0.82 | SIRT2 (0.40) | POLBTP53DPP4DPP7THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884774-B2 | Cyclic hexapeptide derivatives | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1259535-B1 | CYCLIC HEXAPEPTIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-04-13 | — | — | EP | disclosed |