Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7325659 | 0.91 | SIRT2 (0.46) | SIRT2SIRT1MAPTGAALMNA | |
| Trifluoroacetic Acid SCHEMBL7320929 | 0.90 | ALDH1A1 (0.42) | SIRT2SIRT1MAPTGAALMNA | |
| Trifluoroacetic Acid SCHEMBL7318099 | 0.87 | F2RL3 (0.41) | MAPTTHRBTP53DPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL7323148 | 0.87 | LMNA (0.48) | SIRT2SIRT1MAPTLMNATP53 | |
| Trifluoroacetic Acid SCHEMBL7324043 | 0.87 | MTOR (0.42) | SIRT2SIRT1MAPTLMNATP53 | |
| Trifluoroacetic Acid SCHEMBL6132409 | 0.86 | MAPT (0.41) | SIRT2SIRT1MAPTGAALMNA | |
| Trifluoroacetic Acid SCHEMBL7317609 | 0.86 | TP53 (0.41) | SIRT2SIRT1MAPTLMNATP53 | |
| SCHEMBL6135226 | 0.86 | MAPT (0.43) | SIRT2SIRT1MAPTGAATHRB | |
| SCHEMBL6132626 | 0.85 | TP53 (0.46) | MAPTTP53CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL6132355 | 0.84 | MAPT (0.38) | MAPTGAALMNATHRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |