Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324188 | 0.90 | CA12 (0.51) | TP53MAPTCA12CA1CA2 | |
| SCHEMBL7321691 | 0.90 | CA12 (0.51) | TP53MAPTCA12CA1CA2 | |
| SCHEMBL7324602 | 0.90 | CA12 (0.51) | TP53MAPTCA12CA1CA2 | |
| SCHEMBL7318285 | 0.90 | CA12 (0.51) | TP53MAPTCA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL6538606 | 0.88 | TP53 (0.47) | TP53MAPTCA12CA1CA2 | |
| SCHEMBL6132844 | 0.88 | CA12 (0.53) | TP53MAPTCA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL7316392 | 0.87 | TP53 (0.47) | TP53MAPTCA12CA1CA2 | |
| SCHEMBL7350288 | 0.87 | HRH3 (0.63) | TP53MAPTKCNH2HRH3 | |
| SCHEMBL7326355 | 0.86 | HRH3 (0.62) | TP53MAPTKCNH2HRH3 | |
| SCHEMBL7312730 | 0.86 | HRH3 (0.62) | TP53MAPTKCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |