Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | RARB | P10826 | 4/20 | 0.48 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132717 | 0.93 | RARB (0.58) | CA12CA1CA2CA9TP53 | |
| SCHEMBL7326102 | 0.92 | RARB (0.56) | CA12CA1CA2CA9TP53 | |
| SCHEMBL7318285 | 0.90 | CA12 (0.51) | CA12CA1CA2CA9TP53 | |
| SCHEMBL7321691 | 0.90 | CA12 (0.51) | CA12CA1CA2CA9TP53 | |
| SCHEMBL7324188 | 0.90 | CA12 (0.51) | CA12CA1CA2CA9TP53 | |
| SCHEMBL7324602 | 0.90 | CA12 (0.51) | CA12CA1CA2CA9TP53 | |
| SCHEMBL6132534 | 0.88 | TP53 (0.50) | CA12CA1CA2CA9TP53 | |
| SCHEMBL6539767 | 0.86 | MAPT (0.57) | CA12CA1CA2CA9TP53 | |
| SCHEMBL7320722 | 0.82 | PTPN11 (0.51) | CA12CA1CA2CA9TP53 | |
| Trifluoroacetic Acid SCHEMBL7323575 | 0.81 | CA12 (0.46) | CA12CA1CA2CA9TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |