Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132628 | 1.00 | MAPT (0.48) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL6132255 | 0.74 | MAPT (0.51) | MAPTSMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL6132253 | 0.74 | MAPT (0.51) | MAPTSMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL12391039 | 0.73 | ASIC3 (0.50) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL12781692 | 0.73 | MAPT (0.53) | MAPTRAB9AALDH1A1TSHRGAA | |
| SCHEMBL10433612 | 0.73 | MAPT (0.53) | MAPTRAB9AALDH1A1TSHRGAA | |
| SCHEMBL19012391 | 0.73 | MAPT (0.53) | MAPTRAB9AALDH1A1TSHRGAA | |
| SCHEMBL6132558 | 0.72 | KDM4E (0.57) | ALDH1A1HTTGAAKMT2A | |
| SCHEMBL6132555 | 0.72 | KDM4E (0.57) | ALDH1A1HTTGAAKMT2A | |
| SCHEMBL6132808 | 0.72 | KDM4E (0.57) | ALDH1A1HTTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |