Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14901975 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL409154 | 0.79 | NOTUM (0.47) | ALDH1A1HPGDKDM4EPKMGAA | |
| SCHEMBL2967855 | 0.78 | CA12 (0.45) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL15741667 | 0.77 | MAPT (0.53) | ALDH1A1HPGDKDM4EPKMSMN1; SMN2 | |
| SCHEMBL2970267 | 0.77 | NOTUM (0.50) | ALDH1A1HPGDKDM4EPKMGAA | |
| SCHEMBL16925471 | 0.77 | CA1 (0.47) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL6132715 | 0.75 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EPKMGAA | |
| SCHEMBL7086433 | 0.75 | VCAM1 (0.51) | ALDH1A1HPGDKDM4EGAAVCAM1 | |
| SCHEMBL29244614 | 0.74 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EPKMSMN1; SMN2 | |
| SCHEMBL6132307 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |