Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 19/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132775 | 0.89 | MAPT (0.42) | MAPTLMNAPPARATHRBTP53 | |
| SCHEMBL6132850 | 0.87 | MAPT (0.38) | MAPTLMNATHRBTP53GAA | |
| SCHEMBL6132918 | 0.75 | MAPT (0.40) | MAPTLMNATHRBTP53POLB | |
| SCHEMBL6132854 | 0.74 | MAPT (0.39) | MAPTLMNATHRBTP53GAA | |
| SCHEMBL6134755 | 0.74 | MAPT (0.43) | MAPTLMNATHRBTP53GAA | |
| SCHEMBL6132659 | 0.74 | MAPT (0.38) | MAPTLMNATHRBTP53GAA | |
| SCHEMBL6134854 | 0.68 | TP53 (0.45) | MAPTTHRBTP53GAA | |
| SCHEMBL6134753 | 0.67 | MAPT (0.39) | MAPTLMNATHRBTP53GAA | |
| SCHEMBL6132626 | 0.67 | TP53 (0.46) | MAPTPPARATP53POLB | |
| SCHEMBL6134575 | 0.67 | TP53 (0.43) | MAPTTHRBTP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |