Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2941789 | 0.91 | P2RX3 (0.50) | ALDH1A1TSHRFDFT1P2RX3MEN1 | |
| SCHEMBL6132342 | 0.90 | ALDH1A1 (0.54) | ALDH1A1TSHRP2RX3MEN1KMT2A | |
| SCHEMBL20188098 | 0.84 | HPGD (0.65) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL22015905 | 0.84 | HPGD (0.65) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL3457437 | 0.81 | HPGD (0.55) | ALDH1A1TSHRFDFT1MEN1KMT2A | |
| SCHEMBL378276 | 0.81 | TDP1 (0.60) | ALDH1A1TSHRFDFT1MEN1KMT2A | |
| SCHEMBL3067260 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL6134488 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL13328300 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TSHRKMT2AKDM4ELMNA | |
| SCHEMBL378149 | 0.80 | HPGD (0.54) | ALDH1A1TSHRFDFT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |