Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | PTPRF | P10586 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132709 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL6132938 | 0.87 | CSNK2A2 (0.48) | ALDH1A1MAPTRAB9APTPRFPTPN2 | |
| SCHEMBL6132936 | 0.87 | CSNK2A2 (0.48) | ALDH1A1MAPTRAB9APTPRFPTPN2 | |
| SCHEMBL6132481 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL6132480 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL7339724 | 0.81 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL6132728 | 0.80 | MAPT (0.52) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL6132730 | 0.80 | MAPT (0.52) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL6132521 | 0.80 | HDAC3 (0.51) | ALDH1A1KMT2AMEN1GAARAB9A | |
| SCHEMBL6134997 | 0.77 | HRH3 (0.47) | ALDH1A1KMT2AMEN1PDE4DPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |