Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132728 | 1.00 | MAPT (0.52) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL6132481 | 0.85 | ALDH1A1 (0.53) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL6132480 | 0.85 | ALDH1A1 (0.53) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL6132709 | 0.80 | ALDH1A1 (0.43) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL6132711 | 0.80 | ALDH1A1 (0.43) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL6132970 | 0.80 | MAPT (0.52) | MAPTKMT2AALDH1A1KDM4ECA1 | |
| SCHEMBL6132972 | 0.80 | MAPT (0.52) | MAPTKMT2AALDH1A1KDM4ECA1 | |
| SCHEMBL6132380 | 0.78 | ALDH1A1 (0.62) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL6132378 | 0.78 | ALDH1A1 (0.62) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL7341735 | 0.77 | ALDH1A1 (0.60) | MAPTKMT2AALDH1A1MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |