Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 4/20 | 0.59 |
| ▸ | CASP6 | P55212 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132774 | 1.00 | GFER (0.59) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL6132861 | 0.81 | USP2 (0.62) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL6132857 | 0.81 | USP2 (0.62) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL13069950 | 0.79 | MAPT (0.54) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL6132320 | 0.78 | USP2 (0.57) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL6132668 | 0.78 | USP2 (0.57) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL6132666 | 0.78 | USP2 (0.57) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL6132323 | 0.78 | USP2 (0.57) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL82046 | 0.76 | GFER (0.71) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL1128293 | 0.76 | GFER (0.71) | GFERCASP6MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |