Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.43 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12082268 | 0.84 | L3MBTL1 (0.50) | HRH3KDM4ETP53L3MBTL1L3MBTL3 | |
| SCHEMBL1645940 | 0.82 | L3MBTL1 (0.49) | HRH3KDM4ETP53L3MBTL1L3MBTL3 | |
| SCHEMBL7989190 | 0.81 | L3MBTL3 (0.54) | HRH3IRAK4KDM4ETP53L3MBTL1 | |
| SCHEMBL10395267 | 0.80 | L3MBTL3 (0.73) | HRH3KDM4ETP53L3MBTL1L3MBTL3 | |
| SCHEMBL7991862 | 0.79 | L3MBTL3 (0.53) | HRH3IRAK4KDM4ETP53L3MBTL1 | |
| SCHEMBL725292 | 0.79 | L3MBTL3 (0.71) | HRH3KDM4ETP53L3MBTL1L3MBTL3 | |
| SCHEMBL1748901 | 0.78 | KDM4E (0.58) | HRH3KDM4ETP53SMN1; SMN2CHRNA10 | |
| SCHEMBL1647379 | 0.77 | KMT2A (0.62) | KDM4ETP53L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5800431 | 0.77 | KDM4E (0.61) | HRH3KDM4ETP53L3MBTL1L3MBTL3 | |
| SCHEMBL13558248 | 0.75 | HRH3 (0.50) | HRH3KDM4ETP53ALDH1A1CHRNA10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |