Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3107207 | 0.87 | RAB9A (0.76) | RAB9AMAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL17713905 | 0.81 | KDM4E (0.76) | RAB9AMAPTLMNAKDM4ESMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6134403 | 0.79 | USP2 (0.42) | RAB9AMAPTLMNASMN1; SMN2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6134750 | 0.79 | USP2 (0.42) | RAB9AMAPTLMNASMN1; SMN2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6133865 | 0.78 | MAOB (0.40) | RAB9AMAPTLMNACSNK2A2CSNK2B | |
| SCHEMBL6132860 | 0.78 | XIAP (0.48) | RAB9AMAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL6538920 | 0.78 | RAB9A (0.94) | RAB9AMAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7323592 | 0.77 | RAB9A (1.00) | RAB9AMAPTLMNAKDM4ESMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7317798 | 0.77 | CSNK2A2 (0.59) | RAB9AMAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7316179 | 0.77 | NR1H4 (0.65) | TP53HDAC1HDAC2CSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |