Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | DDX3X | O00571 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6132856 | 0.78 | RAB9A (0.62) | XIAPHDAC1HDAC2HDAC6RAB9A | |
| SCHEMBL7319177 | 0.75 | MAPT (0.56) | XIAPHDAC1HDAC2HDAC6RAB9A | |
| SCHEMBL7324575 | 0.75 | MAPT (0.56) | XIAPHDAC1HDAC2HDAC6RAB9A | |
| SCHEMBL7397503 | 0.75 | MAPT (0.56) | XIAPHDAC1HDAC2HDAC6RAB9A | |
| SCHEMBL7317106 | 0.73 | NR1H4 (0.65) | HDAC1HDAC2HDAC6CSNK2A2CSNK2A1 | |
| SCHEMBL7341006 | 0.73 | NR1H4 (0.65) | HDAC1HDAC2HDAC6CSNK2A2CSNK2A1 | |
| SCHEMBL7316607 | 0.73 | NR1H4 (0.65) | HDAC1HDAC2HDAC6CSNK2A2CSNK2A1 | |
| SCHEMBL7316179 | 0.73 | NR1H4 (0.65) | HDAC1HDAC2HDAC6CSNK2A2CSNK2A1 | |
| SCHEMBL678081 | 0.70 | NR1H4 (0.55) | XIAPHDAC1HDAC2HDAC6RAB9A | |
| SCHEMBL19538772 | 0.70 | SMN1; SMN2 (0.55) | XIAPHDAC1HDAC2HDAC6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |