Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | TPH1 | P17752 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132713 | 1.00 | MAPT (0.57) | MAPTRAB9ANPC1ALDH1A1S1PR1 | |
| SCHEMBL7340382 | 0.92 | S1PR1 (0.57) | MAPTRAB9ANPC1ALDH1A1S1PR1 | |
| SCHEMBL6132571 | 0.89 | RARB (0.55) | MAPTRAB9ANPC1S1PR1S1PR3 | |
| SCHEMBL6132663 | 0.89 | RARB (0.55) | MAPTRAB9ANPC1S1PR1S1PR3 | |
| SCHEMBL7331263 | 0.84 | MAPT (0.56) | MAPTRAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL6132386 | 0.84 | MAPT (0.52) | MAPTRAB9ANPC1ALDH1A1S1PR1 | |
| SCHEMBL6132384 | 0.84 | MAPT (0.52) | MAPTRAB9ANPC1ALDH1A1S1PR1 | |
| SCHEMBL14926518 | 0.84 | MAPT (0.70) | MAPTRAB9ANPC1TP53SMN1; SMN2 | |
| SCHEMBL7324195 | 0.83 | MAPT (0.55) | MAPTRAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL6132917 | 0.83 | SMPD1 (0.57) | MAPTRAB9ANPC1TP53CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |