Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TPH1 | P17752 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132663 | 1.00 | RARB (0.55) | RARBS1PR1S1PR3TP53TSHR | |
| SCHEMBL2350982 | 0.91 | RARB (0.70) | RARBS1PR1S1PR3TP53TSHR | |
| SCHEMBL6132713 | 0.89 | MAPT (0.57) | S1PR1S1PR3TP53NR1H4HTT | |
| SCHEMBL6132859 | 0.89 | MAPT (0.57) | S1PR1S1PR3TP53NR1H4HTT | |
| SCHEMBL7341743 | 0.84 | NR1H4 (0.65) | RARBTP53TSHRPLA2G4BNR1H4 | |
| SCHEMBL6132679 | 0.83 | NR1H4 (0.44) | RARBNR1H4TPH1MAPT | |
| SCHEMBL6132909 | 0.83 | NR1H4 (0.44) | RARBNR1H4TPH1MAPT | |
| SCHEMBL18682414 | 0.83 | RARB (0.77) | RARBTP53TSHRPLA2G4BHTT | |
| SCHEMBL7332700 | 0.83 | RARB (0.77) | RARBTP53TSHRPLA2G4BHTT | |
| SCHEMBL7340390 | 0.83 | RARB (0.77) | RARBTP53TSHRPLA2G4BHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |