Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132386 | 1.00 | MAPT (0.52) | MAPTNPC1RAB9AALDH1A1TP53 | |
| SCHEMBL6132679 | 0.91 | NR1H4 (0.44) | MAPTHDAC4HDAC6CA2CA9 | |
| SCHEMBL6132909 | 0.91 | NR1H4 (0.44) | MAPTHDAC4HDAC6CA2CA9 | |
| SCHEMBL6132306 | 0.84 | LMNA (0.51) | MAPTALDH1A1LMNAGRK2MAPK1 | |
| SCHEMBL6132385 | 0.84 | RARB (0.47) | MAPTCA2CA9S1PR1 | |
| SCHEMBL6132713 | 0.84 | MAPT (0.57) | MAPTNPC1RAB9AALDH1A1TP53 | |
| SCHEMBL6132859 | 0.84 | MAPT (0.57) | MAPTNPC1RAB9AALDH1A1TP53 | |
| SCHEMBL6133194 | 0.82 | HDAC4 (0.47) | MAPTNPC1RAB9ATP53ATM | |
| SCHEMBL6132885 | 0.82 | HDAC4 (0.47) | MAPTNPC1RAB9ATP53ATM | |
| SCHEMBL7340382 | 0.76 | S1PR1 (0.57) | MAPTNPC1RAB9AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |