Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6133194 | 1.00 | HDAC4 (0.47) | HDAC4HDAC6HDAC3HDAC1HDAC7 | |
| SCHEMBL6132933 | 0.88 | HDAC3 (0.56) | HDAC4HDAC6HDAC3HDAC1HDAC7 | |
| SCHEMBL6132522 | 0.88 | HDAC3 (0.56) | HDAC4HDAC6HDAC3HDAC1HDAC7 | |
| SCHEMBL6132384 | 0.82 | MAPT (0.52) | HDAC4HDAC6NPC1RAB9AMAPT | |
| SCHEMBL6132386 | 0.82 | MAPT (0.52) | HDAC4HDAC6NPC1RAB9AMAPT | |
| SCHEMBL12243336 | 0.81 | HDAC3 (0.53) | HDAC4HDAC6HDAC3HDAC1HDAC7 | |
| SCHEMBL6132679 | 0.79 | NR1H4 (0.44) | HDAC4HDAC6MAPTCA2CA9 | |
| SCHEMBL6132909 | 0.79 | NR1H4 (0.44) | HDAC4HDAC6MAPTCA2CA9 | |
| SCHEMBL7326769 | 0.76 | HDAC3 (0.59) | HDAC4HDAC6HDAC3HDAC1HDAC7 | |
| SCHEMBL7324486 | 0.76 | HDAC3 (0.67) | HDAC4HDAC6HDAC3HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |