Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441987 | 0.84 | PLAU (0.61) | PLAUALDH1A1TDP1HSD17B10HPGD | |
| SCHEMBL7609777 | 0.84 | TSHR (0.49) | PLAUALDH1A1TDP1HSD17B10HPGD | |
| SCHEMBL30135431 | 0.82 | PLAU (0.59) | PLAUALDH1A1TDP1HSD17B10HPGD | |
| SCHEMBL187375 | 0.82 | PLAU (0.59) | PLAUALDH1A1TDP1HSD17B10HPGD | |
| SCHEMBL11065566 | 0.82 | PLAU (0.44) | PLAUALDH1A1TDP1HSD17B10HPGD | |
| SCHEMBL7119559 | 0.82 | TDP1 (0.58) | PLAUALDH1A1TDP1HSD17B10HPGD | |
| SCHEMBL27753430 | 0.81 | PLAU (0.58) | PLAUALDH1A1TDP1HSD17B10HPGD | |
| SCHEMBL7117378 | 0.79 | CTSB (0.50) | PLAUALDH1A1TDP1HSD17B10HPGD | |
| SCHEMBL18244845 | 0.78 | TDP1 (0.48) | PLAUALDH1A1TDP1HSD17B10HPGD | |
| SCHEMBL9743432 | 0.78 | PLAU (0.54) | PLAUALDH1A1TDP1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250100980-A1 | NOVEL LEUKOTRIENE B4 RECEPTOR INHIBITORS AND USE THEREOF | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2025-03-27 | — | — | US | claimed |
| CN-114751868-B | Diaryl substituted triazole acetic acid compound, and preparation method and application thereof | 山东理工大学 | 2024-04-12 | — | — | CN | claimed |
| WO-2023121022-A1 | NOVEL LEUKOTRIENE B4 RECEPTOR INHIBITORS AND USE THEREOF | 이화여자대학교 산학협력단 | 2023-06-29 | — | — | WO | claimed |
| CN-114751868-A | Diaryl-substituted triazole acetic acid compound and preparation method and application thereof | 山东理工大学 | 2022-07-15 | — | — | CN | claimed |
| EP-3221309-B1 | NOVEL BENZIMIDAZOLE BASED EGFR INHIBITORS | COUNCIL SCIENT IND RES (IN) | 2019-11-13 | — | — | EP | claimed |
| CN-106855519-B | A kind of underground hydrological mercury ion detecting safe tracer agent and preparation method thereof | 詹继峰 | 2019-07-02 | — | — | CN | claimed |
| EP-3253750-B1 | NOVEL FLAVONE BASED EGFR INHIBITORS AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2019-04-10 | — | — | EP | claimed |
| CN-106855519-A | A kind of underground hydrological mercury ion detecting safe tracer agent and preparation method thereof | 詹继峰 | 2017-06-16 | — | — | CN | claimed |
| US-9487540-B2 | Compound for inhibiting the growth and proliferation of human liver cancer cells and method for synthesizing it | ALGHAMDI ZAINAB SAEED (SA) | 2016-11-08 | — | — | US | claimed |
| EP-2385831-A2 | SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT | The UAB Research Foundation (US) | 2011-11-16 | — | — | EP | claimed |
| WO-2010065329-A2 | NANOPARTICLES FOR CANCER TREATMENT | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-06-10 | — | — | WO | claimed |
| US-7732534-B2 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION (JP) | 2010-06-08 | — | — | US | claimed |
| US-20080051519-A1 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION (JP) | 2008-02-28 | — | — | US | claimed |
| US-20080051552-A1 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION | 2008-02-28 | — | — | US | claimed |
| US-20060241178-A1 | Compositions and methods for treating lung cancer | IMMUNEGUARD LLC (US) | 2006-10-26 | — | — | US | claimed |
| WO-2004060365-A1 | COMPOSITIONS AND METHODS FOR TREATING LUNG CANCER | AMERICAN HEALTH FOUNDATION (US) | 2004-07-22 | — | — | WO | claimed |
| US-5684156-A | Process for preparation of clonidine derivatives | ALCON RESEARCH, LTD. | 1997-11-04 | — | — | US | claimed |
| EP-0693055-B1 | NOVEL PROCESS FOR PREPARATION OF CLONIDINE DERIVATIVES | ALCON LAB INC (US) | 1997-05-21 | — | — | EP | claimed |
| EP-0693055-A1 | NOVEL PROCESS FOR PREPARATION OF CLONIDINE DERIVATIVES | ALCON LAB INC (US) | 1996-01-24 | — | — | EP | claimed |
| WO-1995021818-A1 | NOVEL PROCESS FOR PREPARATION OF CLONIDINE DERIVATIVES | ALCON LABORATORIES, INC. (US) | 1995-08-17 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250100980-A1 | NOVEL LEUKOTRIENE B4 RECEPTOR INHIBITORS AND USE THEREOF | LTB4R2, LTB4R, CYSLTR2 | PLAU 473/4885ALDH1A1 2694/4885TDP1 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.