Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.47 |
| ▸ | HTR3B | O95264 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 2/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6132820 | 0.79 | MEN1 (0.52) | HRH3KCNH2HPGD | |
| SCHEMBL6132581 | 0.79 | MAPT (0.54) | HRH3KCNH2KDM1A | |
| SCHEMBL18553743 | 0.79 | ADRB1 (0.56) | HRH3ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL8285653 | 0.78 | HRH3 (0.50) | HRH3KCNH2SIGMAR1HPGD | |
| Hydrochloric Acid SCHEMBL6539081 | 0.77 | ADRB1 (0.54) | HRH3ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL8551038 | 0.77 | ADRB1 (0.62) | HRH3KCNH2ADRB1HTR3EHTR3B | |
| SCHEMBL13437926 | 0.77 | HRH3 (0.81) | HRH3KCNH2 | |
| SCHEMBL3584179 | 0.77 | HRH3 (0.81) | HRH3KCNH2 | |
| SCHEMBL3573919 | 0.77 | HRH3 (0.81) | HRH3KCNH2 | |
| SCHEMBL13437933 | 0.76 | ADRB1 (0.47) | HRH3KCNH2ADRB1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |