Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605746 | 0.78 | CYP1A2 (0.75) | ALDH1A1CYP3A4HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL613010 | 0.76 | ALDH1A1 (0.60) | ALDH1A1CYP3A4HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL5594445 | 0.75 | CYP1A2 (0.64) | ALDH1A1CYP3A4HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL4341824 | 0.75 | CYP1A2 (0.64) | ALDH1A1CYP3A4HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL2852240 | 0.75 | MC5R (0.58) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9850401 | 0.75 | ALDH1A1 (0.50) | ALDH1A1CYP3A4HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL4168758 | 0.73 | ALDH1A1 (0.67) | ALDH1A1CYP3A4HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL11441212 | 0.73 | ALDH1A1 (0.60) | ALDH1A1CYP3A4HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL30436899 | 0.72 | CYP1A2 (0.55) | ALDH1A1CYP3A4HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL8808326 | 0.72 | ALDH1A1 (0.64) | ALDH1A1CYP3A4HSD17B10CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2299275-B1 | Classification of the oncofetal fibronection level for pregnancy-related indications | ADEZA BIOMEDICAL CORP (US) | 2018-03-07 | — | — | EP | disclosed |
| US-9513298-B2 | Methods for detecting oncofetal fibronectin | BANK OF AMERICA, N.A., AS COLLATERAL AGENT | 2016-12-06 | — | — | US | disclosed |
| US-20150044708-A1 | Methods for Detecting Oncofetal Fibronectin | HOLOGIC, INC. | 2015-02-12 | — | — | US | disclosed |
| US-8852872-B2 | Methods for detecting oncofetal fibronectin | HOLOGIC, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-20130171672-A1 | Methods for Detecting Oncofetal Fibronectin | HOLOGIC, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8372581-B2 | Methods for detecting oncofetal fibronectin | CYTYC CORPORATION (US) | 2013-02-12 | — | — | US | disclosed |
| US-20120040356-A1 | Methods for Detecting Oncofetal Fibronectin | CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP | 2012-02-16 | — | — | US | disclosed |
| EP-1778874-B1 | ONCOFETAL FIBRONECTIN AS A MARKER FOR CERVICAL CANCER | ADEZA BIOMEDICAL CORP (US) | 2011-11-23 | — | — | EP | disclosed |
| US-7943294-B2 | Methods for detecting oncofetal fibronectin | HOLOGIC, INC. (US) | 2011-05-17 | — | — | US | disclosed |
| EP-2299275-A2 | Classification of the oncofetal fibronection level for the indication of diseases and other conditions | ADEZA BIOMEDICAL CORPORATION (US) | 2011-03-23 | — | — | EP | disclosed |
| EP-1778874-A2 | ONCOFETAL FIBRONECTIN AS A MARKER FOR DISEASE AND OTHER CONDITIONS AND METHODS FOR DETECTION OF ONCOFETAL FIBRONECTIN | ADEZA BIOMEDICAL CORPORATION (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006026020-A9 | ONCOFETAL FIBRONECTIN AS A MARKER FOR DISEASE AND OTHER CONDITIONS AND METHODS FOR DETECTION OF ONCOFETAL FIBRONECTIN | ADEZA BIOMEDICAL CORP (US) | 2006-07-06 | — | — | WO | disclosed |
| WO-2006026020-A2 | ONCOFETAL FIBRONECTIN AS A MARKER FOR DISEASE AND OTHER CONDITIONS AND METHODS FOR DETECTION OF ONCOFETAL FIBRONECTIN | ADEZA BIOMEDICAL CORPORATION (US) | 2006-03-09 | — | — | WO | disclosed |
| US-20060024724-A1 | Oncofetal fibronectin as a marker for health and disease | CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP | 2006-02-02 | — | — | US | disclosed |
| US-20060024725-A1 | Oncofetal fibronectin as a marker for pregnancy-related indications | THIRD WAVE TECHNOLOGIES, INC. | 2006-02-02 | — | — | US | disclosed |
| US-20060024757-A1 | Detection of oncofetal fibronectin for selection of concepti | CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP | 2006-02-02 | — | — | US | disclosed |
| US-20060024722-A1 | Samples for detection of oncofetal fibronectin and uses thereof | BIOLUCENT, LLC | 2006-02-02 | — | — | US | disclosed |
| US-20060024723-A1 | Methods for detecting oncofetal fibronectin | CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP | 2006-02-02 | — | — | US | disclosed |