Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6133702 | 1.00 | ADRB3 (0.52) | ADRB3ADRB1RAF1BRAFMCHR1 | |
| SCHEMBL6133682 | 0.94 | ADRB3 (0.45) | ADRB3ADRB1RAF1BRAFMCHR1 | |
| SCHEMBL6133687 | 0.94 | ADRB3 (0.45) | ADRB3ADRB1RAF1BRAFMCHR1 | |
| SCHEMBL6134225 | 0.93 | ADRB3 (0.55) | ADRB3ADRB1 | |
| SCHEMBL6134223 | 0.93 | ADRB3 (0.55) | ADRB3ADRB1 | |
| SCHEMBL6134558 | 0.90 | ADRB3 (0.49) | ADRB3ADRB1MCHR1 | |
| SCHEMBL6134556 | 0.90 | ADRB3 (0.49) | ADRB3ADRB1MCHR1 | |
| SCHEMBL6133762 | 0.88 | ADRB3 (0.67) | ADRB3ADRB1 | |
| SCHEMBL6133765 | 0.88 | ADRB3 (0.67) | ADRB3ADRB1 | |
| SCHEMBL6133370 | 0.87 | ADRB3 (0.56) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090669-A1 | Aminoalcohol derivatives as beta-3 adrenergic receptor agonists | ASTELLAS PHARMA INC. (JP) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090669-A1 | Aminoalcohol derivatives as beta-3 adrenergic receptor agonists | ADRB2, ADRB1, ADRB3 | ADRB3 3/4885ADRB1 2/4885RAF1 2228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.