Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 5/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 3/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.37 |
| ▸ | CFD | P00746 | 3/20 | 0.37 |
| ▸ | TPSB2 | P20231 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | F11 | P03951 | 2/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170939 | 0.92 | ADA (0.45) | ADAPTGER1PTGER4PTGER3PTGER2 | |
| Hydrochloric Acid SCHEMBL6134353 | 0.89 | PARP1 (0.39) | ADAPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL6133407 | 0.89 | PTGER1 (0.41) | ADASLC1A5PTGER1PTGER4PTGER3 | |
| SCHEMBL6133343 | 0.89 | ADA (0.42) | ADAPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL6133437 | 0.87 | PTGER1 (0.42) | ADASLC1A5PTGER1PTGER4PTGER3 | |
| SCHEMBL6134089 | 0.86 | CARM1 (0.39) | ADASLC1A5PTGER1PTGER4PTGER3 | |
| SCHEMBL6134135 | 0.86 | ADA (0.39) | ADASLC1A5PTGER1PTGER4PTGER3 | |
| SCHEMBL6172343 | 0.86 | ADA (0.47) | ADAPTGER1PTGER4PTGER3PTGER2 | |
| Hydrochloric Acid SCHEMBL6133493 | 0.85 | PTGER1 (0.38) | ADASLC1A5PTGER1PTGER4PTGER3 | |
| Hydrochloric Acid SCHEMBL6134532 | 0.85 | ABCB1 (0.45) | ADASLC1A5ABCB1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908940-B2 | Imidazole compounds and their use as adenosine deaminase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-21 | — | — | US | claimed |
| US-20040097571-A1 | Imidazole compounds and their use as adenosine deaminase inhibitors | ASTELLAS PHARMA INC. (JP) | 2004-05-20 | — | — | US | claimed |
| US-6908940-B2 | Imidazole compounds and their use as adenosine deaminase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-21 | — | — | US | disclosed |
| US-20040097571-A1 | Imidazole compounds and their use as adenosine deaminase inhibitors | ASTELLAS PHARMA INC. (JP) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097571-A1 | Imidazole compounds and their use as adenosine deaminase inhibitors | ADA, AMPD2, AMPD1 | ADA 1/4885SLC1A5 269/4885PTGER1 1527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.