Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 12/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6133664 | 0.89 | ADORA1 (0.45) | ADORA1CYP1A2ADORA2A | |
| SCHEMBL6134045 | 0.85 | RPS6KA3 (0.44) | ADORA1RPS6KA3CYP1A2ADORA2AKMT2A | |
| SCHEMBL6133302 | 0.83 | CYP1A2 (0.54) | ADORA1CYP1A2ADORA2AKMT2A | |
| SCHEMBL6133973 | 0.82 | ADORA1 (0.55) | ADORA1CYP1A2ADORA2AKMT2AMEN1 | |
| SCHEMBL6134411 | 0.81 | LMNA (0.56) | ADORA1RPS6KA3CYP1A2ADORA2AKMT2A | |
| SCHEMBL6133777 | 0.81 | ADORA1 (0.41) | ADORA1RPS6KA3CYP1A2ADORA2AKMT2A | |
| SCHEMBL6133854 | 0.81 | LMNA (0.46) | ADORA1ADORA2AKMT2AMEN1LMNA | |
| SCHEMBL6133477 | 0.81 | ADORA1 (0.55) | ADORA1ADORA2AKMT2AMEN1LMNA | |
| SCHEMBL6133404 | 0.80 | CYP1A2 (0.37) | ADORA1RPS6KA3CYP1A2ADORA2AKMT2A | |
| SCHEMBL6133660 | 0.80 | PDE4A (0.49) | ADORA1RPS6KA3CYP1A2ADORA2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043315-A1 | Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them | ASTELLAS PHARMA INC. (JP) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043315-A1 | Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them | ADORA2B, ADORA2A, ADORA1 | ADORA1 3/4885RPS6KA3 652/4885CYP1A2 1170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.