Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.65 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135110 | 0.85 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BADORA3HSD17B10 | |
| SCHEMBL6133471 | 0.81 | ADORA1 (0.50) | ADORA2AADORA1ADORA2BKMT2A | |
| SCHEMBL1553927 | 0.79 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3HSD17B10 | |
| SCHEMBL6133617 | 0.79 | ADORA2A (0.43) | ADORA2AADORA1ADORA2BADORA3KMT2A | |
| SCHEMBL6133988 | 0.79 | ADORA2A (0.40) | ADORA2AADORA1ADORA2BALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL3111468 | 0.78 | ADORA2A (0.98) | ADORA2AADORA1ADORA2BADORA3HSD17B10 | |
| Water SCHEMBL2958593 | 0.78 | ADORA2A (0.98) | ADORA2AADORA1ADORA2BADORA3HSD17B10 | |
| SCHEMBL6134042 | 0.78 | ADORA2A (0.39) | ADORA2AADORA1ADORA2BALDH1A1MAPT | |
| SCHEMBL6134686 | 0.78 | GFER (0.43) | ADORA2AADORA1ADORA2BMAPTLMNA | |
| SCHEMBL6133799 | 0.77 | ADORA2A (0.54) | ADORA2AADORA1ADORA2BADORA3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043315-A1 | Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them | ASTELLAS PHARMA INC. (JP) | 2005-02-24 | — | — | US | disclosed |
| WO-2003057689-A1 | AMINOPYRIMIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043315-A1 | Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them | ADORA2B, ADORA2A, ADORA1 | ADORA2A 2/4885ADORA1 3/4885ADORA2B 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.