Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 9/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | LGMN | Q99538 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.40 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135137 | 0.87 | HRH3 (0.45) | CSNK2A2CSNK2A1CSNK2BCHEK1NR1H4 | |
| SCHEMBL6135251 | 0.86 | ALDH1A1 (0.45) | LGMNF12KDM4EUSP2NPC1 | |
| SCHEMBL1663834 | 0.86 | KDM4E (0.53) | LGMNF12KDM4EUSP2NPC1 | |
| Hydrochloric Acid SCHEMBL6132612 | 0.83 | KDM4E (0.50) | LGMNF12CHEK1KDM4EUSP2 | |
| SCHEMBL7340640 | 0.81 | CSNK2A2 (0.54) | CSNK2A2CSNK2A1CSNK2BCHEK1NR1H4 | |
| SCHEMBL7087168 | 0.79 | KDM4E (0.49) | LGMNF12KDM4EUSP2IP6K1 | |
| SCHEMBL6134481 | 0.78 | HRH3 (0.44) | CSNK2A2CSNK2A1CSNK2BCHEK1NR1H4 | |
| SCHEMBL6134209 | 0.78 | HDAC3 (0.47) | LGMNF12NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6134820 | 0.77 | HRH3 (0.47) | CSNK2A2CSNK2A1CSNK2BCHEK1KDM4E | |
| SCHEMBL6373109 | 0.76 | NPC1 (0.58) | CSNK2A2CSNK2A1CSNK2BCHEK1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261177-A1 | Compound | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261177-A1 | Compound | MANBA, MAN2B1, MAN2A1 | CSNK2A2 1527/4885CSNK2A1 961/4885CSNK2B 900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.