SCHEMBL6135563

SCHEMBL6135563

CN1C[C@H](O)[C@@H](O)[C@@H]1CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 8/20 0.87
MGAM O43451 4/20 0.87
AGL P35573 3/20 0.57
GBA1 P04062 4/20 0.50
SI P14410 3/20 0.50
TDP1 Q9NUW8 1/20 0.50
LCT P09848 1/20 0.50
GBA2 Q9HCG7 7/20 0.48
UGCG Q16739 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6135276 1.00 GAA (0.87) GAAMGAMAGLGBA1SI
SCHEMBL9495437 1.00 GAA (0.87) GAAMGAMAGLGBA1SI
SCHEMBL6135315 1.00 GAA (0.87) GAAMGAMAGLGBA1SI
SCHEMBL10824953 1.00 GAA (0.87) GAAMGAMAGLGBA1SI
Hydrochloric Acid SCHEMBL7623702 0.98 GAA (0.83) GAAMGAMAGLGBA1SI
SCHEMBL23503296 0.93 GAA (1.00) GAAMGAMAGLGBA1SI
SCHEMBL2434604 0.93 GAA (1.00) GAAMGAMAGLGBA1SI
SCHEMBL8262434 0.93 GAA (1.00) GAAMGAMAGLGBA1SI
SCHEMBL19227865 0.93 GAA (1.00) GAAMGAMAGLGBA1SI
SCHEMBL11159128 0.93 GAA (1.00) GAAMGAMAGLGBA1SI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6960610-B2 Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases NOVO NORDICK, A/S (DK) 2005-11-01 US claimed
EP-1558245-A2 USE OF GLYCOGEN PHOSPHORYLASE INHIBITORS FOR TREATMENT OF CARDIOVASCULAR DISEASES NOVO NORDISK A/S (DK) 2005-08-03 EP claimed
WO-2004037233-A2 USE OF GLYCOGEN PHOSPHORYLASE INHIBITORS FOR TREATMENT OF CARDIOVASCULAR DISEASES NOVO NORDISK A/S (DK) 2004-05-06 WO claimed
US-20040082641-A1 Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases NOVO NORDISK A/S (DK) 2004-04-29 US claimed
US-20040082646-A1 Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases RYTVED KLAUS ASGER (DK) 2004-04-29 US claimed
EP-0858335-B1 2-ALKYLPYRROLIDINES NOVO NORDISK AS (DK) 2003-03-12 EP claimed
US-6451836-B1 Method of inhibiting liver glycogen phosphorylase with 2-alkylpyrrolidines NOVO NORDISK A/S (DK) 2002-09-17 US claimed
EP-1040827-A2 Use of 2-alkylpyrrolidines for the treatment of diabetes NOVO NORDISK A/S (DK) 2000-10-04 EP claimed
JP-3043430-B2 2000-05-22 JP claimed
EP-0858335-A1 2-ALKYLPYRROLIDINES NOVO NORDISK A/S (DK) 1998-08-19 EP claimed
WO-1997009040-A1 2-ALKYLPYRROLIDINES NOVO NORDISK A/S (DK) 1997-03-13 WO claimed
EP-0322395-B1 HETEROCYCLIC COMPOUNDS FOR INHIBITING VIRUS Monsanto Company (US) 1993-03-24 EP claimed
EP-0322395-A1 Heterocyclic compounds for inhibiting virus Monsanto Company (US) 1989-06-28 EP claimed
US-12378584-B2 Methionine analogue synthesis ENGENES BIOTECH GMBH (AT) 2025-08-05 US disclosed
EP-4547265-A1 TREATING AUTOIMMUNE DISEASES WITH INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR LIGAND CONJUGATED TO AN AGENT Lirum Therapeutics, Inc. (US) 2025-05-07 EP disclosed
WO-2025056760-A1 SURGERY TENT HAVING A REPOSITIONABLE STABILISING ELEMENT SURGITENT GMBH (DE) 2025-03-20 WO disclosed
US-4937357-A ACYLATED DERIVATIVES OF 1,4-DIDEOXY-1,4-IMINO-L-ARABINOL G. D. SEARLE & CO. (US) 1990-06-26 US disclosed
EP-0367747-A2 Dideoxy-L-arabinitol derivatives as antiviral compounds G.D. Searle & Co. (US) 1990-05-09 EP disclosed
EP-0322395-A1 Heterocyclic compounds for inhibiting virus Monsanto Company (US) 1989-06-28 EP disclosed
EP-0322395-A1 Heterocyclic compounds for inhibiting virus Monsanto Company (US) 1989-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082641-A1 Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases PYGM, GYS1, AGL GAA 43/4885MGAM 13/4885AGL 3/4885
US-20040082646-A1 Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases PYGM, GYS1, AGL GAA 45/4885MGAM 12/4885AGL 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.