Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 15/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | ESRRG | P62508 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12640841 | 0.78 | ESR1 (0.60) | ESR1ESR2CYP3A4LMNAAR | |
| SCHEMBL4916330 | 0.78 | ESR1 (0.60) | ESR1ESR2CYP3A4LMNAAR | |
| SCHEMBL505601 | 0.77 | ESR1 (0.65) | ESR1ESR2CYP3A4LMNAAR | |
| SCHEMBL258649 | 0.77 | ESR1 (1.00) | ESR1ESR2CYP3A4LMNAAR | |
| SCHEMBL4704505 | 0.77 | ESR1 (0.65) | ESR1ESR2CYP3A4LMNAAR | |
| SCHEMBL19457909 | 0.76 | ESR1 (0.58) | ESR1ESR2CYP3A4LMNAAR | |
| SCHEMBL49704 | 0.75 | SHBG (0.64) | ESR1ESR2CYP3A4LMNAAR | |
| SCHEMBL2051070 | 0.75 | ESR1 (0.73) | ESR1ESR2CYP3A4LMNAAR | |
| SCHEMBL561786 | 0.75 | ESR1 (0.62) | ESR1ESR2CYP3A4LMNAAR | |
| SCHEMBL19843843 | 0.75 | ESR1 (0.62) | ESR1ESR2CYP3A4LMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409586-A4 | POLYESTER / POLYCARBONATE BLEND COMPOSITION | ENGINEERED PLASTICS CORP (US) | 2005-03-16 | — | — | EP | disclosed |
| EP-1409586-A2 | POLYESTER / POLYCARBONATE BLEND COMPOSITION | Engineered Plastics Corporation (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003004561-A2 | POLYESTER / POLYCARBONATE BLEND COMPOSITION | ENGINEERED PLASTICS CORPORATION (US) | 2003-01-16 | — | — | WO | disclosed |