SCHEMBL6135976

SCHEMBL6135976

C1CN2CCN1CC2.CCCCC1=CC(=C(Br)Br)OC1=O

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.30
BACE1 P56817 1/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1548523 0.91 ACHE (0.35) ACHEBACE1PTPN1
SCHEMBL6138334 0.85 ACHE (0.44) ACHEBACE1PTPN1
SCHEMBL15687665 0.85 ACHE (0.44) ACHEBACE1PTPN1
SCHEMBL15692273 0.78 CDC25A (0.36) ACHEBACE1PTPN1
SCHEMBL6939829 0.75 ALOX5 (0.32)
SCHEMBL4416086 0.75
SCHEMBL14613199 0.74
SCHEMBL6943401 0.74
SCHEMBL15687540 0.74 ALOX5 (0.34)
SCHEMBL15687558 0.74 ALOX5 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1294705-A4 SYNTHESIS OF CYCLIC COMPOUNDS UNISEARCH LTD (AU) 2005-02-09 EP disclosed
EP-1294705-A1 SYNTHESIS OF CYCLIC COMPOUNDS UNISEARCH LIMITED (AU) 2003-03-26 EP disclosed
WO-2002000639-A1 SYNTHESIS OF CYCLIC COMPOUNDS UNISEARCH LIMITED (AU) 2002-01-03 WO disclosed