SCHEMBL6136073

SCHEMBL6136073

CC(C=CC(=O)O)=C(C)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
TP53 P04637 1/20 0.50
EGLN1 Q9GZT9 1/20 0.50
EGLN3 Q9H6Z9 1/20 0.50
HCAR2 Q8TDS4 5/20 0.46
ALDH1A1 P00352 5/20 0.41
TDP1 Q9NUW8 3/20 0.41
ALOX15 P16050 2/20 0.41
RECQL P46063 2/20 0.41
HSD17B10 Q99714 2/20 0.41
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
GABRA5 P31644 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7534023 1.00 TSHR (0.50) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL7535770 1.00 TSHR (0.50) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL11777328 1.00 TSHR (0.50) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL11305485 1.00 TSHR (0.50) TSHRTP53EGLN1EGLN3HCAR2
Fumaric Acid SCHEMBL6697956 0.85 TSHR (0.60) TSHRTP53EGLN1EGLN3HCAR2
Maleic Acid SCHEMBL6697953 0.85 TSHR (0.60) TSHRTP53EGLN1EGLN3HCAR2
Maleic Acid SCHEMBL11123967 0.85 TSHR (0.60) TSHRTP53EGLN1EGLN3HCAR2
Fumaric Acid SCHEMBL29778246 0.85 TSHR (0.60) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL5077222 0.78 FFAR3 (0.32) FFAR3LCKFYN
SCHEMBL34467186 0.77 TSHR (0.56) TSHRTP53EGLN1EGLN3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4741843-A Fluid loss control additives and drilling fluids containing same DIAMOND SHAMROCK CHEMICAL (US) 1988-05-03 US claimed
US-4674574-A USING TERPOLYMERS; FOR GAS FRESH AND SEA WATER DIAMOND SHAMROCK CHEMICALS COMPANY (US) 1987-06-23 US claimed
US-4101326-A Process for making stabilized polyesters used in radiation-sensitive compositions for lithographic plates having improved wear life including hindered phenols and phosphoric acid esters EASTMAN KODAK COMPANY (US) 1978-07-18 US claimed
WO-2015053507-A1 METHOD FOR PRODUCING DIMETHYL TEREPHTHALATE USING ACETYLENE 에스케이케미칼주식회사 2015-04-16 WO disclosed
WO-2015053507-A1 METHOD FOR PRODUCING DIMETHYL TEREPHTHALATE USING ACETYLENE 에스케이케미칼주식회사 2015-04-16 WO disclosed
CN-102725258-A Cyclohexane-1,4-dicarboxylates AMYRIS INC 2012-10-10 CN disclosed
EP-0777492-B1 COMBINATORIAL LIBRARIES OF SUBSTRATE-BOUND CYCLIC ORGANIC COMPOUNDS CHIRON CORP (US) 2005-01-19 EP disclosed
EP-0777492-A4 COMBINATORIAL LIBRARIES OF SUBSTRATE-BOUND CYCLIC ORGANIC COMPOUNDS CHIRON CORP (US) 2002-11-27 EP disclosed
EP-0849636-B1 Photosensitive polymer composition containing photosensitive polyamide and negative working photosensitive element KODAK POLYCHROME GRAPHICS CO (US) 2002-04-10 EP disclosed
US-6270945-B1 BLEND OF PHOTOPOLYMERIZABLE POLYMER AND DYE KODAK POLYCHROME GRAPHICS, LLC 2001-08-07 US disclosed
US-5962189-A Photosensitive composition containing photosensitive polyamide and thiazoline photoinitiator and negative working photosensitive element KODAK POLYCHROME GRAPHICS LLC (US) 1999-10-05 US disclosed
US-3993713-A ATOMIZATION, SPRAY DRYING EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-11-23 US disclosed
US-3991040-A Aromatic imidodicarboxylic acid diallyl esters, prepolymers thereof, cured resins thereof, and processes for producing these TEIJIN LIMITED (JA) 1976-11-09 US disclosed
US-3991112-A Methylated muconic acid hydrazides SUN RESEARCH AND DEVELOPMENT CO. (US) 1976-11-09 US disclosed
US-3991112-A Methylated muconic acid hydrazides SUN RESEARCH AND DEVELOPMENT CO. (US) 1976-11-09 US disclosed
US-3981957-A THERMOPLASTIC POLYMER EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-09-21 US disclosed
US-3957719-A METHOD OF HEAT TREATING AN ETHYLENE CONTAINING POLYMER ELECTRICAL INSULATING COMPOSITION AND PRODUCT FORMED THEREBY GENERAL ELECTRIC COMPANY (US) 1976-05-18 US disclosed
US-3937689-A ALLYL ESTERS OF BENZENE AND NAPHTHALENE DICARBOXYLIC ACIDS TEIJIN LTD. (JA) 1976-02-10 US disclosed
US-3931224-A Aromatic imidodicarboxylic acid diallyl esters, prepolymers thereof, cured resins thereof, and processes for producing these TEIJIN LIMITED (JA) 1976-01-06 US disclosed
US-3775089-A METHYLATED MUCONIC ACID HYDRAZIDES DONNELL A 1973-11-27 US disclosed