SCHEMBL5077222

SCHEMBL5077222

CC=CC(C)=C(C)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12494426 0.82 PTGS1 (0.31) PTGS1
SCHEMBL12494423 0.82 PTGS1 (0.31) PTGS1
SCHEMBL15095681 0.80 TSHR (0.33)
SCHEMBL7534023 0.78 TSHR (0.50) FFAR3LCKFYN
SCHEMBL11777328 0.78 TSHR (0.50) FFAR3LCKFYN
SCHEMBL6136073 0.78 TSHR (0.50) FFAR3LCKFYN
SCHEMBL7535770 0.78 TSHR (0.50) FFAR3LCKFYN
SCHEMBL11305485 0.78 TSHR (0.50) FFAR3LCKFYN
SCHEMBL27817725 0.76 FFAR3 (0.30) FFAR3LCKFYN
SCHEMBL19525323 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1074576-B1 Method for preparing crosslinked organic particles and suspensions DOW CORNING TORAY CO LTD (JP) 2008-05-14 EP claimed
US-20120301525-A1 SILICONE OIL EMULSION, METHOD OF PRODUCING SAME, AND SILICONE OIL COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2012-11-29 US disclosed
EP-1074576-B1 Method for preparing crosslinked organic particles and suspensions DOW CORNING TORAY CO LTD (JP) 2008-05-14 EP disclosed
US-6531542-B1 Emulsification of unsaturated hydrocarbons, polyethers and polysiloxanes in water using emulsifiers, then crosslinking by hydrosilylation in the presence of catalysts to from emulsions used to improve skin feel; cosmetics DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) 2003-03-11 US disclosed
US-6461597-B1 CROSSLINKED SILICONE PARTICLES CONTAINED IN DROPS OF SILICONE OIL DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-10-08 US disclosed
EP-1074575-A2 Spherical crosslinked organic particles, suspensions, and methods of preparing spherical crosslinked organic particles and suspensions. Dow Corning Toray Silicone Co., Ltd. (JP) 2001-02-07 EP disclosed
US-4952634-A Curable carboxylated polymers containing polymeric polyvalent metal salt crosslinking agents SYNTHETIC PRODUCTS COMPANY (US) 1990-08-28 US disclosed
US-4731467-A Process for the preparation of a diester of a 2-butenedioic acid SHELL OIL COMPANY (US) 1988-03-15 US disclosed
EP-0231044-A2 Process for the preparation of a diester of a dicarboxylic acid SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-08-05 EP disclosed
US-4504674-A METAL TREATED RUTHENIUM CATALYST E. I. DUPONT DE NEMOURS & CO. (US) 1985-03-12 US disclosed
US-4307094-A ANTIHYPERTENSIVE AGENTS HOFFMANN-LA ROCHE INC. (US) 1981-12-22 US disclosed
US-4236023-A Preparation of unsaturated monoesters by the catalytic oxidative carbonylation of diolefins with an enol ether or 1-alkoxycycloalkene ATLANTIC RICHFIELD COMPANY (US) 1980-11-25 US disclosed
US-3976723-A CURED BY CONDENSING WITH A POLYVALENT METAL OXIDE ROHM AND HAAS COMPANY (US) 1976-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120301525-A1 SILICONE OIL EMULSION, METHOD OF PRODUCING SAME, AND SILICONE OIL COMPOSITION SQLE, SRM, SOAT2 FFAR3 628/4885LCK 2858/4885FYN 2104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.