SCHEMBL7534023

SCHEMBL7534023

C/C(C=CC(=O)O)=C(\C)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
TP53 P04637 1/20 0.50
EGLN1 Q9GZT9 1/20 0.50
EGLN3 Q9H6Z9 1/20 0.50
HCAR2 Q8TDS4 5/20 0.46
ALDH1A1 P00352 5/20 0.41
TDP1 Q9NUW8 3/20 0.41
ALOX15 P16050 2/20 0.41
RECQL P46063 2/20 0.41
HSD17B10 Q99714 2/20 0.41
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
GABRA5 P31644 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7535770 1.00 TSHR (0.50) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL6136073 1.00 TSHR (0.50) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL11777328 1.00 TSHR (0.50) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL11305485 1.00 TSHR (0.50) TSHRTP53EGLN1EGLN3HCAR2
Fumaric Acid SCHEMBL6697956 0.85 TSHR (0.60) TSHRTP53EGLN1EGLN3HCAR2
Maleic Acid SCHEMBL6697953 0.85 TSHR (0.60) TSHRTP53EGLN1EGLN3HCAR2
Maleic Acid SCHEMBL11123967 0.85 TSHR (0.60) TSHRTP53EGLN1EGLN3HCAR2
Fumaric Acid SCHEMBL29778246 0.85 TSHR (0.60) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL5077222 0.78 FFAR3 (0.32) FFAR3LCKFYN
SCHEMBL34467186 0.77 TSHR (0.56) TSHRTP53EGLN1EGLN3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4101326-A Process for making stabilized polyesters used in radiation-sensitive compositions for lithographic plates having improved wear life including hindered phenols and phosphoric acid esters EASTMAN KODAK COMPANY (US) 1978-07-18 US claimed
EP-0849636-B1 Photosensitive polymer composition containing photosensitive polyamide and negative working photosensitive element KODAK POLYCHROME GRAPHICS CO (US) 2002-04-10 EP disclosed
US-6270945-B1 BLEND OF PHOTOPOLYMERIZABLE POLYMER AND DYE KODAK POLYCHROME GRAPHICS, LLC 2001-08-07 US disclosed
US-5962189-A Photosensitive composition containing photosensitive polyamide and thiazoline photoinitiator and negative working photosensitive element KODAK POLYCHROME GRAPHICS LLC (US) 1999-10-05 US disclosed
US-5925498-A Photosensitive polymer composition and element containing photosensitive polyamide and mixture of acrylates KODAK POLYCHROME GRAPHICS LLC (US) 1999-07-20 US disclosed
US-5879858-A COMPOSITION COMPRISING RESIN CONTAINING UNSATURATED PHOTOCROSSLINKABLE GROUPS, PHOTOPOLYMERIZABLE MONOMER, PHOTOCROSSLINKABLE POLYESTER RESIN, PHOTOINITIATOR KODAK POLYCHROME GRAPHICS, LLC (US) 1999-03-09 US disclosed
US-5821032-A A PHOTOCURABLE FORMULATION CONTAINS ETHYLENICALLY UNSATURATED PHOTOCROSSLINKABLE GROUPS, AN ETHYLENICALLY UNSATURATED PHOTOPOLYMERIZABLE MONOMER, A CROSSLINKABLE POLYESTER, CROSSLINKABLE STYRENE-MALEIC ANHYDRIDE AND PHOTOINITIATOR KODAK POLYCHROME GRAPHICS, LLC (US) 1998-10-13 US disclosed
EP-0849636-A1 Photosensitive polymer composition containing photosensitive polyamide and negative working photosensitive element EASTMAN KODAK COMPANY (US) 1998-06-24 EP disclosed
EP-0576622-B1 LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK CO (US) 1997-11-05 EP disclosed
EP-0472228-B1 Radiation-sensitive composition containing a vinyl pyrrolidone polymer and use thereof in lithographic printing plates EASTMAN KODAK CO (US) 1997-09-10 EP disclosed
US-4640886-A ANODIZED, SILICATED ALUMINUM SUPPORT, RADIATION SENSITIVE POLYESTER, BENZOIC ACID LAYERS TO IMPROVE INCUBATION STABILITY EASTMAN KODAK COMPANY (US) 1987-02-03 US disclosed
EP-0055897-B1 PROCESS FOR CAPTURE AND STORAGE OF LIGHT ENERGY BY ENDOERGIC ISOMERIZATIONS THE STANDARD OIL COMPANY (US) 1986-11-26 EP disclosed
EP-0199467-A1 Polyesters comprising recurring photoconductive and photocrosslinkable units and elements thereof EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-10-29 EP disclosed
US-4609606-A LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 1986-09-02 US disclosed
EP-0070898-B1 IMAGE-FORMING COMPOSITIONS CONTAINING PIGMENTS AND IONIC POLYESTER DISPERSING AGENTS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-10-16 EP disclosed
EP-0123493-A1 Photochemical conversion and storage of light energy by photoisomerization of compounds such as norbornadiene and its derivatives THE STANDARD OIL COMPANY (US) 1984-10-31 EP disclosed
US-4419437-A SULFONIMIDE-CONTAINING AROMATIC DICARBOXYLIC ACID EASTMAN KODAK COMPANY (US) 1983-12-06 US disclosed
US-4394858-A PHOTOCATALYSTS COMPRISING METAL CARBONYL COMPOUNDS STANDARD OIL COMPANY (US) 1983-07-26 US disclosed
EP-0055897-A2 Process for capture and storage of light energy by endoergic isomerizations THE STANDARD OIL COMPANY (US) 1982-07-14 EP disclosed
US-4101326-A Process for making stabilized polyesters used in radiation-sensitive compositions for lithographic plates having improved wear life including hindered phenols and phosphoric acid esters EASTMAN KODAK COMPANY (US) 1978-07-18 US disclosed