SCHEMBL6136114

SCHEMBL6136114

CC(=O)[C@@]1(O)[C@H](O)[C@@H](CO)O[C@@]1(C(C)=O)n1ccc(=O)[nH]c1=O

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.42
SLC28A2 O43868 1/20 0.42
SLC29A1 Q99808 1/20 0.42
SLC28A3 Q9HAS3 1/20 0.42
P2RY14 Q15391 3/20 0.34
P2RY2 P41231 4/20 0.32
P2RY4 P51582 3/20 0.32
P2RY6 Q15077 6/20 0.31
CRBN Q96SW2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2337871 0.85 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL2337859 0.85 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL60518 0.82 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL4259316 0.81 SLC28A1 (0.38) SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL30286899 0.81 SLC28A1 (0.36) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL4653180 0.81 TK1 (0.40) ALDH1A1LMNA
SCHEMBL851503 0.80 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL31000081 0.80 SLC28A1 (0.37) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL29084627 0.79 SLC28A1 (0.42) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
Uridine SCHEMBL1347808 0.79 SLC28A1 (0.56) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1402071-A4 METHODS AND PRODUCTS FOR ANALYZING NUCLEIC ACIDS BASED ON METHYLATION STATUS US GENOMICS INC (US) 2005-12-14 EP disclosed
EP-1402071-A2 METHODS AND PRODUCTS FOR ANALYZING NUCLEIC ACIDS BASED ON METHYLATION STATUS U.S. Genomics, Inc. (US) 2004-03-31 EP disclosed
WO-2002101353-A2 METHODS AND PRODUCTS FOR ANALYZING NUCLEIC ACIDS BASED ON METHYLATION STATUS U.S. GENOMICS, INC. (US) 2002-12-19 WO disclosed