Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847231 | 0.86 | — | — | |
| SCHEMBL466674 | 0.85 | ADRA2A (0.41) | ADRA2AADRA2BADRA2C | |
| SCHEMBL24565419 | 0.82 | — | — | |
| SCHEMBL18069695 | 0.79 | NOS3 (0.38) | NOS3NOS1NOS2ADRA2AADRA2B | |
| SCHEMBL29733228 | 0.79 | NOS3 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL21033815 | 0.77 | NOS3 (0.37) | NOS3NOS1NOS2ADRA2AADRA2B | |
| SCHEMBL1648862 | 0.76 | NOS3 (0.40) | NOS3NOS1NOS2ADRA2AADRA2B | |
| SCHEMBL29733444 | 0.76 | CYP2D6 (0.38) | NOS3NOS1NOS2 | |
| SCHEMBL1648860 | 0.74 | NOS3 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL1648965 | 0.73 | NOS3 (0.38) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737231-B2 | THERMAL STABILIZED RESIN COMPOSITIONS | KOLON INC (KR) | 2005-11-02 | — | — | EP | disclosed |
| EP-0737231-B1 | THERMAL STABILIZED RESIN COMPOSITIONS | KOLON INC (KR) | 2000-03-08 | — | — | EP | disclosed |
| EP-0737231-A1 | THERMAL STABILIZED RESIN COMPOSITIONS | KOLON INDUSTRIES, INC. (KR) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018181-A1 | THERMAL STABILIZED RESIN COMPOSITIONS | KOLON INDUSTRIES, INC. (KR) | 1995-07-06 | — | — | WO | disclosed |