SCHEMBL6136344

SCHEMBL6136344

CCC(C)(C1=NC(C)CO1)C1=NC(C)CO1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17087997 0.79 ADRA2A (0.37) ADRA2AADRA2B
SCHEMBL918048 0.79 ADRA2A (0.37) ADRA2AADRA2B
SCHEMBL19051429 0.79 ADRA2A (0.37) ADRA2AADRA2B
Bromide SCHEMBL7105757 0.75 ADRA2A (0.35) ADRA2AADRA2B
SCHEMBL14602161 0.72 ADRA2A (0.33) ADRA2AADRA2B
SCHEMBL2549969 0.69 ADRA2A (0.32) ADRA2AADRA2B
SCHEMBL15291801 0.67 KCNN4 (0.35) ADRA2AADRA2B
SCHEMBL19266731 0.67 KCNN4 (0.35) ADRA2AADRA2B
SCHEMBL17551978 0.63 ADRA2A (0.42) ADRA2AADRA2BMAPT
SCHEMBL17552003 0.63 ADRA2A (0.42) ADRA2AADRA2BMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0737231-B2 THERMAL STABILIZED RESIN COMPOSITIONS KOLON INC (KR) 2005-11-02 EP disclosed
EP-0737231-B1 THERMAL STABILIZED RESIN COMPOSITIONS KOLON INC (KR) 2000-03-08 EP disclosed
US-5849820-A Thermal stabilized resin compositions KOLON INDUSTRIES, INC. (KR) 1998-12-15 US disclosed
EP-0737231-A1 THERMAL STABILIZED RESIN COMPOSITIONS KOLON INDUSTRIES, INC. (KR) 1996-10-16 EP disclosed
WO-1995018181-A1 THERMAL STABILIZED RESIN COMPOSITIONS KOLON INDUSTRIES, INC. (KR) 1995-07-06 WO disclosed