Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2742839 | 1.00 | ADRA2A (0.42) | ADRA2AADRA2BMAPTNPC1GAA | |
| SCHEMBL17551978 | 1.00 | ADRA2A (0.42) | ADRA2AADRA2BMAPTNPC1GAA | |
| SCHEMBL381475 | 0.83 | MEN1 (0.46) | MAPTNPC1 | |
| SCHEMBL11254435 | 0.82 | MAPT (0.34) | ADRA2AADRA2BMAPT | |
| SCHEMBL2119357 | 0.79 | MAPT (0.55) | ADRA2AADRA2BMAPTNPC1GAA | |
| SCHEMBL2044082 | 0.78 | MAPT (0.54) | ADRA2AADRA2BMAPTNPC1GAA | |
| SCHEMBL7386839 | 0.78 | MAPT (0.47) | MAPTNPC1 | |
| SCHEMBL5176371 | 0.76 | KDM4E (0.44) | ADRA2AADRA2BMAPTNPC1GAA | |
| SCHEMBL14154741 | 0.76 | KDM4E (0.44) | ADRA2AADRA2BMAPTNPC1GAA | |
| SCHEMBL12731994 | 0.76 | MAPT (0.51) | MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423195-B1 | HEXACOORDINATED RUTHENIUM OR OSMIUM METAL CARBENE METATHESIS CATALYSTS | CALIFORNIA INST OF TECHN (US) | 2016-03-02 | — | — | EP | disclosed |