Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 16/20 | 0.66 |
| ▸ | ITGA4 | P13612 | 16/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683165 | 0.88 | ITGA4 (0.67) | ITGB1ITGA4MEN1KMT2AGAA | |
| SCHEMBL14558520 | 0.87 | ITGB1 (0.58) | ITGB1ITGA4KMT2A | |
| SCHEMBL7392556 | 0.86 | ITGB3 (0.55) | ITGB1ITGA4MEN1KMT2AITGB3 | |
| SCHEMBL14558547 | 0.86 | ITGA4 (0.57) | ITGB1ITGA4 | |
| SCHEMBL7868788 | 0.86 | ITGB1 (0.60) | ITGB1ITGA4MEN1KMT2AGAA | |
| SCHEMBL14558536 | 0.86 | ITGA4 (0.53) | ITGB1ITGA4MEN1KMT2A | |
| SCHEMBL7420147 | 0.85 | ITGA4 (0.57) | ITGB1ITGA4MEN1KMT2A | |
| SCHEMBL14222078 | 0.85 | MEN1 (0.59) | ITGB1ITGA4MEN1KMT2AGAA | |
| SCHEMBL4675624 | 0.85 | MEN1 (0.59) | ITGB1ITGA4MEN1KMT2AGAA | |
| SCHEMBL5701009 | 0.84 | ITGA4 (0.59) | ITGB1ITGA4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042279-B1 | SUBSTITUTED BETA-ALANINES | AVENTIS PHARMA LTD (GB) | 2005-03-02 | — | — | EP | disclosed |
| US-6352977-B1 | ALANINE WITH PRODRUGS | AVENTIS PHARMA LIMITED (GB) | 2002-03-05 | — | — | US | disclosed |
| EP-1042279-A1 | SUBSTITUTED BETA-ALANINES | Aventis Pharma Limited (GB) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999054321-A1 | SUBSTITUTED DIAMINES AND THEIR USE AS CELL ADHESION INHIBITORS | AVENTIS PHARMA LIMITED (GB) | 1999-10-28 | — | — | WO | disclosed |
| WO-1999033789-A1 | SUBSTITUTED β-ALANINES | AVENTIS PHARMA LIMITED (GB) | 1999-07-08 | — | — | WO | disclosed |