Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 9/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136535 | 1.00 | ALDH1A1 (0.38) | ALDH1A1GAATDP1MCL1NR1H4 | |
| SCHEMBL4797124 | 0.90 | MCL1 (0.43) | MCL1POLB | |
| SCHEMBL4318171 | 0.90 | MCL1 (0.43) | MCL1POLB | |
| SCHEMBL6136813 | 0.88 | MCL1 (0.41) | ALDH1A1GAATDP1MCL1NR1H4 | |
| SCHEMBL6136812 | 0.88 | MCL1 (0.41) | ALDH1A1GAATDP1MCL1NR1H4 | |
| SCHEMBL4326643 | 0.78 | MCL1 (0.49) | MCL1 | |
| SCHEMBL4326640 | 0.78 | MCL1 (0.49) | MCL1 | |
| SCHEMBL15380544 | 0.71 | CHRM3 (0.36) | ALDH1A1TDP1MCL1 | |
| SCHEMBL4325029 | 0.67 | ALDH1A1 (0.36) | ALDH1A1GAATDP1POLBNPSR1 | |
| SCHEMBL4325028 | 0.67 | ALDH1A1 (0.36) | ALDH1A1GAATDP1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991654-B1 | NOVEL 2-(IMINOMETHYL)AMINO-PHENYL DERIVATIVES, PREPARATION, APPLICATION AS MEDICINES AND COMPOSITIONS CONTAINING SAME | SOD CONSEILS RECH APPLIC (FR) | 2005-06-15 | — | — | EP | disclosed |