Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 14/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 3/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136813 | 1.00 | MCL1 (0.41) | MCL1MEN1GALR3HTTKMT2A | |
| SCHEMBL4326643 | 0.91 | MCL1 (0.49) | MCL1BCL2BCL2L1 | |
| SCHEMBL4326640 | 0.91 | MCL1 (0.49) | MCL1BCL2BCL2L1 | |
| SCHEMBL6136535 | 0.88 | ALDH1A1 (0.38) | MCL1MEN1KMT2ANR1H4ALDH1A1 | |
| SCHEMBL6136539 | 0.88 | ALDH1A1 (0.38) | MCL1MEN1KMT2ANR1H4ALDH1A1 | |
| SCHEMBL4318171 | 0.78 | MCL1 (0.43) | MCL1 | |
| SCHEMBL4797124 | 0.78 | MCL1 (0.43) | MCL1 | |
| SCHEMBL4317053 | 0.77 | MMP2 (0.52) | MCL1KMT2ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL4317049 | 0.77 | MMP2 (0.52) | MCL1KMT2ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL4795920 | 0.77 | MMP2 (0.52) | MCL1KMT2ASMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991654-B1 | NOVEL 2-(IMINOMETHYL)AMINO-PHENYL DERIVATIVES, PREPARATION, APPLICATION AS MEDICINES AND COMPOSITIONS CONTAINING SAME | SOD CONSEILS RECH APPLIC (FR) | 2005-06-15 | — | — | EP | disclosed |
| EP-0991654-A1 | NOVEL 2-(IMINOMETHYL)AMINO-PHENYL DERIVATIVES, PREPARATION, APPLICATION AS MEDICINES AND COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998058934-A1 | NOVEL 2-(IMINOMETHYL)AMINO-PHENYL DERIVATIVES, PREPARATION, APPLICATION AS MEDICINES AND COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-12-30 | — | — | WO | disclosed |