Phenol

Phenol

SCHEMBL6136544

C=C(C)C(=O)OCCC.Oc1ccccc1.Oc1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.53
GAA P10253 1/20 0.53
TSHR P16473 6/20 0.50
LMNA P02545 3/20 0.50
ALDH1A1 P00352 6/20 0.49
TDP1 Q9NUW8 3/20 0.49
ESR1 P03372 2/20 0.49
CHRM1 P11229 1/20 0.49
SLC6A2 P23975 1/20 0.49
KDR P35968 1/20 0.49
THRB P10828 1/20 0.47
POLB P06746 2/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 1/20 0.41
ELANE P08246 1/20 0.41
MAPK1 P28482 2/20 0.39
HPGD P15428 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL112435 0.88 TSHR (0.71) SMN1; SMN2TSHRLMNAALDH1A1TDP1
Phenol SCHEMBL28875314 0.87 TDP1 (0.46) SMN1; SMN2GAATSHRLMNAALDH1A1
Phenol SCHEMBL6751269 0.86 ALDH1A1 (0.56) SMN1; SMN2GAATSHRALDH1A1TDP1
Phenol SCHEMBL6136311 0.86 ALDH1A1 (0.56) SMN1; SMN2GAATSHRALDH1A1TDP1
Benzoic Acid SCHEMBL23114213 0.85 POLB (0.58) SMN1; SMN2GAATSHRLMNAALDH1A1
Phthalic Acid SCHEMBL3317643 0.85 ALDH1A1 (0.54) SMN1; SMN2GAATSHRLMNAALDH1A1
SCHEMBL10690073 0.84 ELANE (0.56) SMN1; SMN2GAATSHRLMNAALDH1A1
Phenetole SCHEMBL27680105 0.83 TDP1 (0.52) SMN1; SMN2GAATSHRLMNAALDH1A1
Styrene SCHEMBL5864400 0.83 TSHR (0.46) SMN1; SMN2GAATSHRLMNAALDH1A1
Acetic Acid SCHEMBL21001126 0.82 TSHR (0.64) SMN1; SMN2GAATSHRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0726739-B2 DENTAL PROSTHESIS WITH COMPOSITE SUPPORT SHELL AND COATING, PREIMPREGNATED FABRIC PART AND MANUFACTURING METHOD BILLET GILLES (FR) 2005-03-09 EP disclosed
EP-0726739-B1 DENTAL PROSTHESIS WITH COMPOSITE SUPPORT SHELL AND COATING, PREIMPREGNATED FABRIC PART AND MANUFACTURING METHOD BILLET GILLES (FR) 1998-08-26 EP disclosed
EP-0726739-A1 DENTAL PROSTHESIS WITH COMPOSITE SUPPORT SHELL AND COATING, PREIMPREGNATED FABRIC PART, MANUFACTURING METHOD AND MACHINE Billet, Gilles (FR) 1996-08-21 EP disclosed
WO-1995008300-A1 DENTAL PROSTHESIS WITH COMPOSITE SUPPORT SHELL AND COATING, PREIMPREGNATED FABRIC PART, MANUFACTURING METHOD AND MACHINE BILLET GILLES (FR) 1995-03-30 WO disclosed