Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157491 | 0.90 | RECQL (0.48) | RORBRECQLMAPTPOLBLMNA | |
| Formic Acid SCHEMBL5157620 | 0.86 | RORB (0.44) | RORBRECQLMAPTPOLBLMNA | |
| SCHEMBL5342361 | 0.83 | MAPT (0.54) | RORBRECQLMAPTGAAPOLB | |
| SCHEMBL14419284 | 0.80 | POLB (0.51) | RORBPOLBRORC | |
| SCHEMBL6103175 | 0.80 | POLB (0.66) | RECQLMAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL3486347 | 0.78 | MAPT (0.61) | MAPTGAAPOLBTSHRLMNA | |
| SCHEMBL10396396 | 0.77 | RECQL (0.53) | RECQLMAPTTSHRLMNAMAPK1 | |
| SCHEMBL2705425 | 0.77 | RECQL (0.65) | RORBRECQLMAPTSMN1; SMN2TSHR | |
| SCHEMBL14419421 | 0.76 | POLB (0.55) | MAPTPOLBLMNAHTT | |
| SCHEMBL27430859 | 0.76 | MAPT (0.52) | MAPTPOLBLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133474-A4 | 3-SUBSTITUTED-4-ARYLQUINOLIN-2-ONE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2005-02-16 | — | — | EP | disclosed |
| EP-1133474-A1 | 3-SUBSTITUTED-4-ARYLQUINOLIN-2-ONE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000034244-A1 | 3-SUBSTITUTED-4-ARYLQUINOLIN-2-ONE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-06-15 | — | — | WO | disclosed |