Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128828 | 0.87 | MAPT (0.62) | POLBMAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL11306685 | 0.86 | LMNA (0.63) | POLBMAPTGAAHTTNPSR1 | |
| SCHEMBL29229971 | 0.86 | POLB (0.64) | POLBMAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL10713056 | 0.85 | RORC (0.56) | POLBKDM4ETSHRLMNAALDH1A1 | |
| SCHEMBL23409104 | 0.85 | POLB (0.56) | POLBMAPTSMN1; SMN2KDM4EHTT | |
| SCHEMBL14419510 | 0.84 | KCNMA1 (0.64) | POLBMAPTSMN1; SMN2HSD17B10ALOX15 | |
| SCHEMBL11590852 | 0.84 | POLB (0.67) | POLBMAPTMAPK1HTTNPSR1 | |
| SCHEMBL11289664 | 0.84 | MEN1 (0.71) | POLBMAPTKDM4EHTTNPSR1 | |
| SCHEMBL30785077 | 0.83 | TP53 (0.66) | POLBMAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL8751765 | 0.83 | HPGD (0.69) | POLBMAPTSMN1; SMN2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10092786-B2 | Fire extinguishing composition comprising aldoketones compound | XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) | 2018-10-09 | — | — | US | claimed |
| US-20160332016-A1 | Fire Extinguishing Composition Comprising Aldoketones Compound | NANO FIRE, LLC | 2016-11-17 | — | — | US | claimed |
| US-10092786-B2 | Fire extinguishing composition comprising aldoketones compound | XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) | 2018-10-09 | — | — | US | disclosed |
| EP-3095487-A1 | FIRE EXTINGUISHING COMPOSITION COMPRISING ALDOKETONES COMPOUND | Xi'an J&R Fire Fighting Equipment Co., Ltd. (CN) | 2016-11-23 | — | — | EP | disclosed |
| US-20160332016-A1 | Fire Extinguishing Composition Comprising Aldoketones Compound | NANO FIRE, LLC | 2016-11-17 | — | — | US | disclosed |
| US-20130267712-A1 | AROMATIC KETONE SYNTHESIS WITH AMIDE REAGENTS AND RELATED REACTIONS | BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY (US) | 2013-10-10 | — | — | US | disclosed |
| US-20130267712-A1 | AROMATIC KETONE SYNTHESIS WITH AMIDE REAGENTS AND RELATED REACTIONS | BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY (US) | 2013-10-10 | — | — | US | disclosed |
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |
| US-20060004062-A1 | Compounds for inhibiting insulin secretion and methods related thereto | MITOKOR (US) | 2006-01-05 | — | — | US | disclosed |
| US-6958352-B2 | Compounds for inhibiting insulin secretion and methods related thereto | SMITHKLINE BEECHAM CORPORATION (US) | 2005-10-25 | — | — | US | disclosed |
| EP-1472214-A2 | COMPOUNDS FOR INHIBITING INSULIN SECRETION AND METHODS RELATED THERETO | SmithKline Beecham Corporation (US) | 2004-11-03 | — | — | EP | disclosed |
| US-20040044049-A1 | Compounds for inhibiting insulin secretion and methods related thereto | MITOKOR | 2004-03-04 | — | — | US | disclosed |
| WO-2003066035-A2 | COMPOUNDS FOR INHIBITING INSULIN SECRETION AND METHODS RELATED THERETO | SMITHKLINE BEECHAM CORPORATION (US) | 2003-08-14 | — | — | WO | disclosed |
| US-4006243-A | FUNGICIDE, BACTERICIDE, YEAST | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004062-A1 | Compounds for inhibiting insulin secretion and methods related thereto | IAPP, GPR119, INSR | POLB 4146/4885MAPT 3794/4885SMN1; SMN2 2997/4885 |
| US-20040044049-A1 | Compounds for inhibiting insulin secretion and methods related thereto | IAPP, GPR119, IRS1 | POLB 3780/4885MAPT 3914/4885SMN1; SMN2 2753/4885 |
| US-20130267712-A1 | AROMATIC KETONE SYNTHESIS WITH AMIDE REAGENTS AND RELATED REACTIONS | NAAA, AADAC, NISCH | POLB 2837/4885MAPT 2706/4885SMN1; SMN2 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.