SCHEMBL6136835

SCHEMBL6136835

CCCC(C)[Si](OC)(OC)C(C)CCC

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
CHRM1 P11229 1/20 0.31
AKR1A1 P14550 1/20 0.31
CHRM3 P20309 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27133140 0.78 TSHR (0.32) TSHRCHRM1AKR1A1CHRM3HTR2A
SCHEMBL2400701 0.78 TSHR (0.32) TSHRCHRM1AKR1A1CHRM3HTR2A
SCHEMBL106580 0.77 TSHR (0.30) TSHR
SCHEMBL8852509 0.76 TSHR (0.31) TSHR
SCHEMBL8852617 0.76 TSHR (0.31) TSHR
SCHEMBL15302738 0.74 HSD17B10 (0.31)
SCHEMBL28441849 0.74
SCHEMBL224076 0.70 OPRM1 (0.31)
SCHEMBL15302773 0.70 ADRB2 (0.33) TSHR
SCHEMBL17048006 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199913-A1 METHOD FOR SUPPRESSING COLLAPSE OF THREE-DIMENSIONAL STRUCTURE TOKYO OHKA KOGYO CO., LTD. (JP) 2024-06-20 US disclosed
WO-2022213043-A1 METHOD FOR SUPPRESSING COLLAPSE OF THREE-DIMENSIONAL STRUCTURE TOKYO OHKA KOGYO CO., LTD. (JP) 2022-10-06 WO disclosed
US-8791221-B2 Addition-curable metallosiloxane compound DAICEL CORPORATION (JP) 2014-07-29 US disclosed
EP-2650319-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND Daicel Corporation (JP) 2013-10-16 EP disclosed
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND DAICEL CORPORATION (JP) 2013-10-10 US disclosed
EP-0903356-B1 CRYSTALLINE POLYPROPYLENE, PROCESS FOR PREPARING THE SAME, POLYPROPYLENE COMPOSITION, AND THERMOFORMED ARTICLE MITSUI CHEMICALS INC (JP) 2005-09-07 EP disclosed
EP-1026198-B1 Polypropylene resin composition and injection-molded article thereof MITSUI CHEMICALS INC (JP) 2004-12-15 EP disclosed
US-6759475-B2 MECHANICAL PROPERTIES AND IN THE FLOWABILITY UPON INJECTION MOLDING AND CAN SERVE FOR A MATERIAL FOR EXHIBITING BETTER APPEARANCE MITSUI CHEMICALS, INC. (JP) 2004-07-06 US disclosed
EP-0896969-B1 Process for preparing solid titanium catalyst component, olefin polymerization catalyst, and olefin polymerization process MITSUI CHEMICALS INC (JP) 2004-03-03 EP disclosed
EP-0916701-B1 CRYSTALLINE POLYPROPYLENE RESIN COMPOSITION MITSUI CHEMICALS INC (JP) 2004-02-25 EP disclosed
EP-0641807-A2 Olefin polymerization catalyst and process for preparing polypropylene and a propylene block copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-03-08 EP disclosed
EP-0636650-A1 Propylene polymer compositions MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-02-01 EP disclosed
EP-0634455-A1 Polypropylene resin composition and the use of the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-01-18 EP disclosed
EP-0605180-A1 Polypropylene composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-07-06 EP disclosed
EP-0585869-A1 Solid titanium catalyst component for olefin polymerization, process for preparing the same, catalyst for olefin polymerization and process for olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-03-09 EP disclosed
EP-0582278-A2 Method for producing a polyolefin TOSOH CORPORATION (JP) 1994-02-09 EP disclosed
US-5244989-A METHOD FOR PRODUCING A STEREOSPECIFIC POLYOLEFIN TOSOH CORPORATION (JP) 1993-09-14 US disclosed
EP-0530814-A1 Method for producing a stereospecific polyolefin TOSOH CORPORATION (JP) 1993-03-10 EP disclosed
EP-0504744-A2 Method for producing a stereospecific polyolefin TOSOH CORPORATION (JP) 1992-09-23 EP disclosed
EP-0475134-A2 Method for producing a stereospecific polyolefin Tosoh Corporation (JP) 1992-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND B2M, MSI2, MNS1 TSHR 4702/4885CHRM1 149/4885AKR1A1 1621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.