Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704839 | 0.89 | PRF1 (0.40) | ALOX15HSD17B10KDM4EMEN1THRB | |
| SCHEMBL7812170 | 0.83 | DPP4 (0.41) | ALOX15KDM4EMEN1THRBKMT2A | |
| SCHEMBL7812222 | 0.75 | DPP4 (0.33) | MEN1KMT2AAPPDPP4CYP3A4 | |
| SCHEMBL6136905 | 0.75 | PDE10A (0.52) | ALOX15HSD17B10KDM4EMEN1THRB | |
| SCHEMBL6136925 | 0.75 | CA1 (0.47) | ALOX15HSD17B10KDM4EMEN1THRB | |
| Hydrochloric Acid SCHEMBL6137029 | 0.73 | PDE10A (0.50) | ALOX15HSD17B10KDM4EMEN1THRB | |
| SCHEMBL6136853 | 0.73 | KDM4E (0.44) | ALOX15HSD17B10KDM4EMEN1THRB | |
| SCHEMBL6136958 | 0.73 | LCK (0.38) | ALOX15HSD17B10KDM4EMEN1THRB | |
| SCHEMBL6136945 | 0.72 | ALOX15 (0.50) | ALOX15HSD17B10KDM4EMEN1THRB | |
| Hydrochloric Acid SCHEMBL7198371 | 0.71 | ALOX15 (0.49) | ALOX15HSD17B10KDM4EMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153917-B1 | p-Aminophenol derivatives and colorants containing them | WELLA AG (DE) | 2005-04-13 | — | — | EP | claimed |
| US-6592631-B2 | Useful as developer compounds in oxidation dye compositions for keratin fibers. | WELLA AG (DE) | 2003-07-15 | — | — | US | claimed |
| US-20010054207-A1 | p-aminophenol derivative compounds and dye compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2001-12-27 | — | — | US | claimed |
| EP-1153917-A1 | p-Aminophenol derivatives and colorants containing them | Wella Aktiengesellschaft (DE) | 2001-11-14 | — | — | EP | claimed |
| EP-1153917-B1 | p-Aminophenol derivatives and colorants containing them | WELLA AG (DE) | 2005-04-13 | — | — | EP | disclosed |
| US-6592631-B2 | Useful as developer compounds in oxidation dye compositions for keratin fibers. | WELLA AG (DE) | 2003-07-15 | — | — | US | disclosed |
| US-20010054207-A1 | p-aminophenol derivative compounds and dye compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2001-12-27 | — | — | US | disclosed |
| EP-1153917-A1 | p-Aminophenol derivatives and colorants containing them | Wella Aktiengesellschaft (DE) | 2001-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010054207-A1 | p-aminophenol derivative compounds and dye compositions containing same | KRT18, AASDHPPT, S100P | ALOX15 2954/4885HSD17B10 702/4885KDM4E 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.