Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672547 | 1.00 | KDM4E (0.60) | KDM4ETDP1ALDH1A1SMN1; SMN2ABCB1 | |
| SCHEMBL5495031 | 0.99 | KDM4E (0.58) | KDM4ETDP1ALDH1A1SMN1; SMN2ABCB1 | |
| Citric Acid SCHEMBL1672543 | 0.88 | KDM4E (0.59) | KDM4ETDP1ALDH1A1SMN1; SMN2ABCB1 | |
| Citric Acid SCHEMBL5487236 | 0.88 | KDM4E (0.59) | KDM4ETDP1ALDH1A1SMN1; SMN2ABCB1 | |
| Citric Acid SCHEMBL5495834 | 0.88 | KDM4E (0.59) | KDM4ETDP1ALDH1A1SMN1; SMN2ABCB1 | |
| Citric Acid SCHEMBL1672548 | 0.88 | KDM4E (0.59) | KDM4ETDP1ALDH1A1SMN1; SMN2ABCB1 | |
| Citric Acid SCHEMBL5495033 | 0.87 | KDM4E (0.57) | KDM4ETDP1ALDH1A1SMN1; SMN2ABCB1 | |
| Citric Acid SCHEMBL5495022 | 0.87 | KDM4E (0.57) | KDM4ETDP1ALDH1A1SMN1; SMN2ABCB1 | |
| SCHEMBL5488903 | 0.86 | KDM4E (0.58) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| Citric Acid SCHEMBL5494395 | 0.79 | KDM4E (0.60) | KDM4ETDP1ALDH1A1SMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453816-A4 | PHENOXY AMINE COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2005-02-09 | — | — | EP | disclosed |
| EP-1453816-A2 | PHENOXY AMINE COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003045306-A2 | PHENOXY AMINE COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2003-06-05 | — | — | WO | disclosed |