Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL5494395 | 0.89 | KDM4E (0.60) | KDM4ESMN1; SMN2MEN1NPC1RAB9A | |
| Citric Acid SCHEMBL5488896 | 0.89 | KDM4E (0.60) | KDM4ESMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL1672547 | 0.86 | KDM4E (0.60) | KDM4ESMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL6137121 | 0.86 | KDM4E (0.60) | KDM4ESMN1; SMN2MEN1NPC1RAB9A | |
| Pramoxine SCHEMBL28549519 | 0.85 | ALDH1A1 (0.68) | KDM4ESMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL5495031 | 0.84 | KDM4E (0.58) | KDM4ESMN1; SMN2MEN1NPC1RAB9A | |
| Citric Acid SCHEMBL5487236 | 0.79 | KDM4E (0.59) | KDM4ESMN1; SMN2MEN1NPC1RAB9A | |
| Citric Acid SCHEMBL5495834 | 0.79 | KDM4E (0.59) | KDM4ESMN1; SMN2MEN1NPC1RAB9A | |
| Citric Acid SCHEMBL1672548 | 0.79 | KDM4E (0.59) | KDM4ESMN1; SMN2MEN1NPC1RAB9A | |
| Citric Acid SCHEMBL1672543 | 0.79 | KDM4E (0.59) | KDM4ESMN1; SMN2MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453816-B1 | PHENOXY AMINE COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2013-09-18 | — | — | EP | disclosed |
| US-7297794-B2 | Phenoxy amine compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-11-20 | — | — | US | disclosed |
| US-20050119502-A1 | Phenoxy amine compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119502-A1 | Phenoxy amine compounds and compositions for delivering active agents | PNMT, SLC5A7, PHOSPHO1 | KDM4E 1807/4885SMN1; SMN2 57/4885MEN1 1089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.