Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137870 | 0.81 | NR4A2 (0.40) | PARP1ACLYEGLN1LMNAPOLB | |
| SCHEMBL10713217 | 0.81 | PARP1 (0.47) | DPP4PARP1ACLYKDM5AKDM4C | |
| SCHEMBL13544495 | 0.79 | PARP1 (0.42) | DPP4PARP1ACLYALDH1A1KDM4E | |
| SCHEMBL29894129 | 0.79 | PARP1 (0.42) | DPP4PARP1ACLYALDH1A1KDM4E | |
| SCHEMBL24754415 | 0.77 | SMN1; SMN2 (0.39) | PARP1ACLYKDM5AKDM4EEGLN1 | |
| SCHEMBL1080823 | 0.77 | PARP1 (0.41) | DPP4PARP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1081560 | 0.76 | CA12 (0.47) | DPP4PARP1ALDH1A1KDM4EEGLN1 | |
| SCHEMBL1081796 | 0.76 | EGLN1 (0.46) | DPP4PARP1ACLYKDM4CALDH1A1 | |
| SCHEMBL4535246 | 0.74 | DPP4 (0.44) | DPP4PARP1ACLYALKALDH1A1 | |
| SCHEMBL6137724 | 0.72 | POLB (0.36) | DPP4PARP1ACLYALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515956-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1515956-A1 | PEPTIDE DEFORMYLASE INHIBITORS | Smithkline Beecham (US) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003104209-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-18 | — | — | WO | disclosed |