Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137382 | 0.78 | — | — | |
| SCHEMBL2419510 | 0.77 | MEN1 (0.31) | — | |
| SCHEMBL6137841 | 0.75 | CRBN (0.32) | — | |
| SCHEMBL4853543 | 0.70 | CYP24A1 (0.33) | — | |
| SCHEMBL6152154 | 0.65 | DRD3 (0.32) | — | |
| SCHEMBL2417565 | 0.65 | ESR2 (0.55) | — | |
| SCHEMBL5904516 | 0.65 | ESR2 (0.55) | — | |
| SCHEMBL4849090 | 0.64 | ESR2 (0.52) | — | |
| SCHEMBL2423359 | 0.64 | CYP24A1 (0.31) | — | |
| SCHEMBL2416248 | 0.63 | HTR2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257264-A4 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1257264-A1 | ESTROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001082923-A1 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2001-11-08 | — | — | WO | disclosed |